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![]() 756 People Lost in total 66572 lbs = 29.11 % Give us permission to add your before & after Weight Loss Photos | ![]() |
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| | #1 (permalink) |
| Guru In Training Join Date: Mar 2006 Location: NJ
Posts: 333
Weight Statistics 3/14/06 Start Date:
4' 11"
Height:
239 lb Start Weight:
119 lb Current Weight:
120 lb Goal Weight:
120 lb Weight Loss:
-1 lb Lb Left to Lose:
50.2092050209 % % Lost:
Body Mass Index 48.2668773341 BMI Start:
24.0324619362 BMI Current:
24.2344153979 BMI Goal:
Weight Loss Method Roux en Y Gastric Bypass |
NEW YORK (Reuters Health) - In what could become a new weapon in the battle of the bulge, scientists on Monday reported initial success with an experimental vaccine for obesity. The researchers found that when they gave rats a vaccine against a "hunger hormone" called ghrelin, the animals were able to live the dream of eating what they wanted without packing on body fat. The findings, published online by the Proceedings of the National Academy of Sciences, suggest a whole new approach to weight loss. It's a long way, however, from success in rats to similar results in people. More research in animals and more data on safety will be needed before an obesity vaccine is widely tested in humans, according to Dr. Kim Janda of the Scripps Research Institute in La Jolla, California. One of the next steps will be to see whether ghrelin vaccination helps already obese rodents shed pounds, Janda told Reuters Health. If a vaccine were to become a reality for humans, it would be aimed at those obese individuals who continually "yo-yo" through diet and exercise, he noted. Secreted primarily by the stomach, ghrelin is one of the hormones that help regulate appetite, metabolism and weight. Ghrelin levels rise before a meal, putting the brakes on calorie burning and fat breakdown, then decline after a person eats. The hormone promotes weight gain and fat storage. Janda and his colleagues aimed to decrease the hormone's activity with an anti-ghrelin vaccine. To do that, they created three ghrelin-recognizing antigens -- proteins that elicit an immune reaction. When Janda's team administered their antigens to rats, they found that two of the antigens were able to bind to the active form of ghrelin, which then triggered the animals' immune systems to produce antibodies against the hormone. "We're training the immune system to recognize ghrelin," Janda said. This immune reaction apparently had effects on the animals' metabolism. Despite having free access to food and eating as much as their unvaccinated mates, the immunized rats gained less weight and boasted leaner, less flabby physiques. That the weight effects came without diet changes was a surprise, Janda said. It means that the ghrelin vaccine acted on metabolism, and not appetite, he explained. "They were eating the same, but still losing weight -- which is pretty cool." Still, the human body's control of hunger, metabolism and weight is very complex, Janda noted. A highly integrated system involving the brain, nerves and numerous hormones strives to keep body weight stable, especially when calorie intake drops -- a fact that "wasn't a problem" back in the hunter-gatherer days of scarce food supplies, Janda pointed out. Whether a ghrelin vaccine can safely and effectively alter this system remains to be seen. SOURCE: Proceedings of the National Academy of Sciences Early Edition, online July 31, 2006.
__________________ Jolie ![]() RNY 3/14/06 239/65/174 |
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| | Weight Loss Surgery Insurance |
| | #2 (permalink) |
| Seasoned Veteran Join Date: Jan 2006 Location: SOMEPLACE LONG ISLAND, NY
Posts: 6,756
Weight Statistics June 1, 2005 Start Date:
Height: 310 lb Start Weight:
167 lb Current Weight:
159 lb Goal Weight:
143 lb Weight Loss:
8 lb Lb Left to Lose:
46.1290322581 % % Lost:
Body Mass Index 51 BMI Start:
27 BMI Current:
Weight Loss Method Roux en Y Gastric Bypass |
YES I heard it on the news tonight here... BUT after my problems i have from REDUX even if FDA approved I wouldnt be quick to try anything new! I have minor permenent heart problems from those diet pills. SO i would proceed with anything with caution but it is hopeful. PROBABLY will take a long time to get thru our system.
__________________ LISA ![]() http://w5.photobucket.com/widgets/dy...164/fr1endly2/ LAP RNY Gastric Bypass |
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| | #3 (permalink) |
| Guru In Training Join Date: May 2006 Location: In the country
Posts: 336
Weight Statistics August 2006 Surgery Date:
Height: 210 lb Start Weight:
141 lb Current Weight:
125 lb Goal Weight:
69 lb Weight Loss:
16 lb Lb Left to Lose:
32.8571428571 % % Lost:
August 2007 Goal Date:
Body Mass Index 38 BMI Start:
25 BMI Current:
22 BMI Goal:
Weight Loss Method Roux en Y Gastric Bypass |
May not even come to pass. If it does, we may not even be around to enjoy it.
__________________ |
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| | #4 (permalink) |
| Super Moderator |
I'm with wannbe here. I've seen enough trumpets blowing with experimetal animals, only to see the balloon deflate when they are moved to humans, if they ever are, and it takes years and years to get there. Another new finding is that researchers have found the genes that regulate the "hunger time clock" in rats which may help in regulating obesity, but it's going to be a long step from rats to humans. If you can be patient enough to wait for results to come out for humans so you can use them, then you are also sure to have the patience to consolidate the new eating habits you need to make with your surgery.
__________________ "In every job that must be done, there is an element of fun." ![]() Just a li'l bit 'bout myself |
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| | #5 (permalink) |
| Seasoned Veteran Join Date: Mar 2006 Location: NYC the best place in the world to live!
Posts: 2,986
Weight Statistics Halloween 2005 Start Date:
4' 11"
Height:
212 lb Start Weight:
127 lb Current Weight:
130 lb Goal Weight:
85 lb Weight Loss:
-3 lb Lb Left to Lose:
40.0943396226 % % Lost:
Body Mass Index 42.8141338696 BMI Start:
25.6480896294 BMI Current:
26.2539500144 BMI Goal:
Weight Loss Method Roux en Y Gastric Bypass |
Ok lets see...Obese rodents... ME, Obese rodents.... Me, Obese rodents....... ME.....Yes ok if it works on obese rodents it must work for me too.....LOL I dont trust any of those things anymore. I too was on the redux as Lisa was but thank god i didnt stay on long enough to cause any damage. Love Ya |
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| | #6 (permalink) |
| Super Moderator Join Date: Oct 2005 Location: illinois
Posts: 510
Weight Statistics 9/12/05 Start Date:
9/12/05 Surgery Date:
Height: 317 lb Start Weight:
184 lb Current Weight:
150 lb Goal Weight:
133 lb Weight Loss:
34 lb Lb Left to Lose:
41.9558359621 % % Lost:
09/12/07 Goal Date:
Body Mass Index 51 BMI Start:
29 BMI Current:
24 BMI Goal:
Weight Loss Method Roux en Y Gastric Bypass |
hmmmmm....most of my problem was this...i didn't eat usually because i was hungry...just cause it was there or triggered by stress and emotions...don't think that would have helped me at all.like the others said...probly won't make it far. huggs christy
__________________ ChristyBlue surgery 9/12/05 open RNY BMI 51/29 315/185/150 130 pounds lost
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